Effects of Oral Supplement Containing L-Histidine and Antioxidants on the Skin Barrier Function and Systemic Inflammation in Rosacea
Trial Parameters
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Brief Summary
The purpose of this study is to evaluate how supplementation will alter the skin and the gut barrier and inflammation in those with rosacea.
Eligibility Criteria
Inclusion Criteria: * Males and females 30 to 70 years of age * The presence of mild to moderate rosacea (erythematotelangiectatic or papulopustular) * High sensitivity C-reactive protein (hs-CRP) that is greater than or equal to 1.0 mg/L Exclusion Criteria: * The presence of severe rosacea as noted by the investigator global assessment. * Those who are unwilling to discontinue oral supplementation, or supplement ingredients found in the study's oral product 1 month prior to enrollment. * Discontinuation of oral L-glutamine or L-glutamine containing supplement 1 month prior to enrollment * Those who are unwilling to discontinue topical benzoyl peroxide or retinoids for 2 weeks prior to enrollment. * Those who are unwilling to keep their facial regimen the same throughout the study. * Individuals who have been on an oral antibiotic within the previous one month. * Individuals who are pregnant or breastfeeding. * Individuals who have changed any of their hormonal based contraception or t