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Recruiting NCT06467552

Effects of Nutritional Support on Postoperative Delirium

Trial Parameters

Condition Postoperative Delirium
Sponsor Yonsei University
Study Type INTERVENTIONAL
Phase N/A
Enrollment 314
Sex ALL
Min Age 65 Years
Max Age N/A
Start Date 2024-06
Completion 2028-05-12
Interventions
control groupNucare Curact group

Brief Summary

This study is a prospective, single-center, randomized controlled trial to compare whether applying nutritional supplementation therapy before and after surgery in elderly patients aged 65 years or older undergoing non-cardiac surgery can reduce the incidence of postoperative delirium.

Eligibility Criteria

Inclusion Criteria: * Elderly patients aged 65 and above. * Patients undergoing non-cardiac major surgery in thoracic surgery, lung cancer surgery, multi-level spinal surgery in neurosurgery and orthopedics, or liver cancer surgery in hepatobiliary and pancreatic surgery, under general anesthesia with an expected surgery duration of 2 hours or more. * Patients scheduled for arterial catheterization. * Patients who are able to take oral intake from postoperative day #1. Exclusion Criteria: * Patients with uncontrolled systemic conditions such as diabetes, hypertension, renal disease, liver disease, and other systemic illnesses. * Those with visual impairment. * Patients with cognitive impairment based on the Mini-Mental State Examination for Dementia Screening criteria. * Individuals experiencing difficulty in communication. * Those diagnosed with neurological disorders (such as brain hemorrhage, stroke, brain tumor, dementia, Parkinson's disease, cognitive impairment, depression, etc.)

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