NCT06025292 Effects of Lean Pork Loin Intake on Protein Homeostasis and Glucose Regulation in Prediabetic Adults
| NCT ID | NCT06025292 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University of Arkansas |
| Condition | Hyperglycaemia (Non Diabetic) |
| Study Type | INTERVENTIONAL |
| Enrollment | 20 participants |
| Start Date | 2024-09-11 |
| Primary Completion | 2026-05-31 |
Trial Parameters
Eligibility Fast-Check
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Brief Summary
We will be directly comparing a high-quality protein diet composed primarily of lean pork loin (PORK) to a lower-quality plant-based protein diet (PLANT) in individuals with prediabetes on muscle and whole-body protein turnover and glucose regulation.
Eligibility Criteria
Inclusion Criteria: * 1\. Males and females ages 40-65 years. * 2\. BMI 25 to ≤40 kg/m2 (or body fat % ≥25% in males or ≥36% in females) * 3\. Capable of providing informed consent. * 4\. COVID-19 negative and/or asymptomatic. * 5\. Willing to abstain from drinking alcohol or consuming marijuana and CBD products during the 4-day study meal period * 6\. HbA1c: 5.7-6.4% or fasting glucose 100-125 mg/dL Exclusion Criteria: * 1\. Participant who does not/will not eat animal protein sources. * 2\. Allergy to wheat, soy, or common ingredients in plant-based protein products. * 3\. Body mass index \<25 kg/m2 or \>40 kg/m2. * 4\. Hemoglobin \<10g/dL at screening. * 5\. Platelets \<150,000/uL at screening. * 6\. History of chemotherapy or radiation therapy for cancer in the 6 months prior to enrollment. * 7\. History of gastrointestinal bypass/reduction surgery. * 8\. Pregnant or lactating individuals. * 9\. History of a chronic inflammatory disease (e.g. Lupus, Crohn's disease) * 10\. Currentl