NCT06888544 Effects of High-Intensity Interval Training on Bone Health in Hong Kong Older Women
| NCT ID | NCT06888544 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Hong Kong Baptist University |
| Condition | Osteopenia |
| Study Type | INTERVENTIONAL |
| Enrollment | 48 participants |
| Start Date | 2024-10-16 |
| Primary Completion | 2026-02-28 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 48 participants in total. It began in 2024-10-16 with a primary completion date of 2026-02-28.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Osteoporosis is an age-related disease, characterized by a decreased bone mass and an increased risk of fragility fractures. Osteoporosis leads to increasing mortality, disabilities, morbidity of chronic pain, and the cost of health and social care, as well as decreasing the quality of life from reduced independence and hindered physical, mental, and social well-being. A recent review and meta-analysis, investigating the association between physical activity and osteoporosis prevention in elderly people, indicated that the traditional exercise interventions (i.e., resistance training) were undertaken for 60+ mins, 2-3 times/week for 7+ months. However, participation rates remain low in these exercise programs among older adults, in part due to a need for specialized equipment and correct techniques to prevent injury. In addition, low motivation and associated compliance with such conventional exercise is problematic among older adults. Considering there is little evidence of HIIT benefits related to older women with osteopenia, the current study aims to evaluate the effectiveness of a 24-week HIIT intervention on bone mineral density, bone turnover markers and other health-related outcomes among Hong Kong Chinese older women.
Eligibility Criteria
Inclusion Criteria: * • 60 to 74 years at the start date of the project * diagnosed with osteopenia by DXA scan screening with a BMD at the femoral neck or total hip or lumbar spine between -1 and -2.5 SD T-score below the average values * Passing the PAR-Q plus screening or with the physician's approval for readiness to participate in high-intensity exercise * Above the average level of 2-mins stepping showing competent aerobic fitness * No restriction on physical mobility * No cognitive impairment, as determined by the Chinese version of the Mini-Mental Status Examination (i.e., score \< 24) * No previous substantial experiences in practicing HIIT. The written informed consent form will be collected from each participant Exclusion Criteria: * • Severe chronic disease restricting high-intensity exercise * Having cognition impairment regarded by specialists * checked through medical records at HA Go app platform in the past 6 months, have concurrent medical conditions (e.g., thyrotoxicosis or hyperparathyroidism, Paget's disease, renal disease, diabetes, knee or hip osteoarthritis) and use medications (e.g., corticosteroids, estrogen, thyroxine, thiazide diuretics, or antiretroviral agents) known to affect bone metabolism during past 2 years * any condition with osteoporosis, osteoporotic fractures * current smoker * alcohol 3 or more units per day.
Contact & Investigator
Yanping Duan
PRINCIPAL INVESTIGATOR
Hong Kong Baptist University; Department of Sport, Physical Education and Health
Frequently Asked Questions
Who can join the NCT06888544 clinical trial?
This trial is open to female participants only, aged 60 Years or older, up to 74 Years, studying Osteopenia. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06888544 currently recruiting?
Yes, NCT06888544 is actively recruiting participants. Contact the research team at duanyp@hkbu.edu.hk for enrollment information.
Where is the NCT06888544 trial being conducted?
This trial is being conducted at China, China.
Who is sponsoring the NCT06888544 clinical trial?
NCT06888544 is sponsored by Hong Kong Baptist University. The principal investigator is Yanping Duan at Hong Kong Baptist University; Department of Sport, Physical Education and Health. The trial plans to enroll 48 participants.