NCT06981663 Effects of Fibres Combined With Probiotics on Uric Acid in an ex Vivo Fermentation Model
| NCT ID | NCT06981663 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Örebro University, Sweden |
| Condition | Hyperuricemia |
| Study Type | OBSERVATIONAL |
| Enrollment | 15 participants |
| Start Date | 2025-06-12 |
| Primary Completion | 2026-12 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 15 participants in total. It began in 2025-06-12 with a primary completion date of 2026-12.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
In this study, we will collect faecal samples from individuals with hyperuricaemia (assessed by blood test) and perform in vitro faecal fermentation studies to assess how probiotics in combination with fibres affect urate metabolism in these faecal samples.
Eligibility Criteria
Inclusion Criteria: 1. Signed informed consent prior to any study-related procedures 2. Age 18-80 years old 3. BMI range 18.5-35 kg/m2 4. Blood uric acid above 0.36 mmol/L (6 mg/dl) 5. Willing to abstain from regular consumption of probiotic supplements or food products containing probiotic bacteria (including fermented food and beverages), until collection of faecal material 6. Willing to abstain from regular consumption of supplements and medications known to alter gastrointestinal function or inflammatory status during the study, until collection of faecal material Exclusion Criteria: 1. Diagnosis of type 1 and/or type 2 diabetes 2. Diagnosed inflammatory bowel disease (IBD) 3. Current diagnosis of psychiatric disease/s or syndromes 4. Current diagnosis of neurodegenerative disease 5. Current pregnancy or breastfeeding 6. History of complicated gastrointestinal surgery 7. Systemic use of antibiotics and/or steroid medication in the last 4 months prior to inclusion 8. Regular use of any non-steroidal anti-inflammatory drug (NSAID) for the last 2 months 9. Consumption of any NSAID within 3 days of sample collection 10. Current (or within the last 4 weeks prior to study start) use of probiotic supplementation 11. Any condition or intake of medication which could substantially interfere with the outcome of the study, as decided by the principal investigator's discretion 12. After being included in the study and until collection of faecal material, starting any medication or treatment that could potentially influence the study participation and/or study analysis
Contact & Investigator
Frequently Asked Questions
Who can join the NCT06981663 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 80 Years, studying Hyperuricemia. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06981663 currently recruiting?
Yes, NCT06981663 is actively recruiting participants. Contact the research team at julia.konig@oru.se for enrollment information.
Where is the NCT06981663 trial being conducted?
This trial is being conducted at Örebro, Sweden.
Who is sponsoring the NCT06981663 clinical trial?
NCT06981663 is sponsored by Örebro University, Sweden. The trial plans to enroll 15 participants.