NCT07238634 Effects of DMI vs Bobath on Neuromuscular Development in CP
| NCT ID | NCT07238634 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Lahore University of Biological and Applied Sciences |
| Condition | Dynamic Movement Intervention |
| Study Type | INTERVENTIONAL |
| Enrollment | 58 participants |
| Start Date | 2026-01-05 |
| Primary Completion | 2026-06-10 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 58 participants in total. It began in 2026-01-05 with a primary completion date of 2026-06-10.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Cerebral palsy (CP) is a leading cause of permanent motor disability in children, resulting from non-progressive disturbances to the developing brain. Prematurity and low birth weight are major risk factors, with infants under 1500 g having a markedly higher risk. Spastic CP is the most common subtype, and spastic diplegia accounts for 30-40% of cases, primarily affecting the lower limbs and trunk control. CP prevalence has declined in high-income countries but remains higher in low- and middle-income regions, including Pakistan. Beyond clinical challenges, CP imposes a substantial lifelong economic burden. Current management follows the ICF framework, emphasizing function, participation, and independence. Traditional approaches such as the Bobath method show limited evidence compared with task-oriented therapies. Dynamic Movement Intervention (DMI) is a neuroplasticity-based, task-oriented approach emphasizing repetitive functional activities. Trunk-focused dynamic training has shown superior improvements in balance and gross motor function. However, comparative evidence between DMI and Bobath therapy in young children is limited, necessitating further research using validated outcome measures.
Eligibility Criteria
Inclusion Criteria: * Diagnosed with spastic diplegic cerebral palsy. * Gross Motor Function Measurement Scale (GMFC) level I to III. * Children who have head control. * Ability to understand and follow simple instructions. Exclusion Criteria: * Visual or hearing impairments (e.g., cataract, myopia, deafness). * Cognitive problems impacting participation. * Uncontrolled convulsions or recent seizure activity. * Orthopedic surgeries of the lower limbs, such as dorsal rhizotomy within the last year.
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07238634 clinical trial?
This trial is open to participants of all sexes, aged 2 Years or older, up to 4 Years, studying Dynamic Movement Intervention. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07238634 currently recruiting?
Yes, NCT07238634 is actively recruiting participants. Contact the research team at atiqaniamat09@gmail.com for enrollment information.
Where is the NCT07238634 trial being conducted?
This trial is being conducted at Lahore, Pakistan.
Who is sponsoring the NCT07238634 clinical trial?
NCT07238634 is sponsored by Lahore University of Biological and Applied Sciences. The trial plans to enroll 58 participants.