NCT04307238 Effects of Different Types of General Anesthesia on Postoperative Pupillary Reactivity
| NCT ID | NCT04307238 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Medical University of Vienna |
| Condition | Pupillary Reflex Impaired |
| Study Type | INTERVENTIONAL |
| Enrollment | 108 participants |
| Start Date | 2020-03-09 |
| Primary Completion | 2026-03-10 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 108 participants in total. It began in 2020-03-09 with a primary completion date of 2026-03-10.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Objective: To compare the effects of volatile and intravenous anesthetics on pupillary function after general anesthesia using a portable infrared pupillometer. Design: A monocentric, prospective, double blinded randomized study. Patients: Patients who require elective Ear, Nose and Throat (ENT) surgery under general anesthesia. Interventions: Patients undergoing elective ENT surgery will be assigned to intravenous versus inhalative anesthesia and pupillometric parameters monitored postoperative, using an infrared pupillometer. Outcomes measures: Reported pupillometric parameters after intravenous and inhalative anesthesia. The purpose of this study is to compare general anesthesia techniques (volatile, intravenous) on postoperative changes in pupillary reactivity by using infrared pupillometry.
Eligibility Criteria
Inclusion Criteria: * Patients aged ≥ 18 and ≤99 years * ASA I-II * Patients undergoing elective ENT surgery under general anesthesia Exclusion Criteria: * Patients aged \< 18 and \>99 years * consumption of antidepressants, tranquilizer, psychotropic medications * history of mental illness, neurosurgery, neurological or psychiatric disease * ophthalmologic disease * preexisting cognitive impairment * Patients with drug dependence, alcoholism * the patients' inability to follow procedures * implanted electronic medical devices
Contact & Investigator
Frequently Asked Questions
Who can join the NCT04307238 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 99 Years, studying Pupillary Reflex Impaired. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT04307238 currently recruiting?
Yes, NCT04307238 is actively recruiting participants. Contact the research team at marita.windpassinger@meduniwien.ac.at for enrollment information.
Where is the NCT04307238 trial being conducted?
This trial is being conducted at Vienna, Austria.
Who is sponsoring the NCT04307238 clinical trial?
NCT04307238 is sponsored by Medical University of Vienna. The trial plans to enroll 108 participants.