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Recruiting NCT07259460
Effects of Dexmedetomidine Target Controlled Infusion on Patient State Index Values and Electroencephalographic Spectrum During Total Intravenous Anesthesia With Propofol
Trial Parameters
Condition Adjuvants, Anesthesia
Sponsor University of Padova
Study Type OBSERVATIONAL
Phase N/A
Enrollment 60
Sex FEMALE
Min Age 18 Years
Max Age 80 Years
Start Date 2025-12-01
Completion 2026-06-30
Brief Summary
Dexmedetomidine Target Controlled infusion (TCI, Dyck model) effects on Neuromonitoring during Total Intravenous Anesthesia (TIVA) with Propofol and Remifentanil TCI (Eleveld model) has not been investigate yet. Authors aim to investigate its effect on Patient State index (PSi), the power spectrum EEG, the Analgesia Nociception Index (ANI) and pupillometry values during maintenance during TIVA-TCI with Propofol, Remifentanil and Dexmedetomidine.
Eligibility Criteria
Inclusion Criteria: * Undergo general anaesthesia with Targeted Controlled Infusion of Propofol and Rmifntanil (Eleveld model) and Dexmedetomidine (Dyck model) Exclusion Criteria: * Neurological disease * Psychiatric disease * Obesity * Regional anesthesia performed