NCT04281979 Effects of a Specific Substance in Smokers
| NCT ID | NCT04281979 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Oregon Health and Science University |
| Condition | Smoking |
| Study Type | INTERVENTIONAL |
| Enrollment | 60 participants |
| Start Date | 2020-02-25 |
| Primary Completion | 2025-12-31 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 60 participants in total. It began in 2020-02-25 with a primary completion date of 2025-12-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Although rates of cigarette use are declining, the proportion of nondaily smokers is rising, particularly among young adults. Among young adults, nondaily smoking is associated with negative health consequences and, for some, may lead to the establishment of life-long smoking patterns. The goal of this project is to understand the behavioral, psychological and neurobiological factors that contribute to cigarette use in nondaily smokers to aid the development of tailored evidence-based interventions.
Eligibility Criteria
Inclusion Criteria: * Participants must be 21-40 years old * Right-handed * Fluent in English * Report smoking cigarettes or e-cigarettes 1-27 days in the past month * Report binge drinking based on NIAAA criteria (5 or more drinks per occasion for males, 4 or more drinks per occasion for females) at least 1 time in the past 90 days without adverse incident Exclusion Criteria: * Seeking treatment for substance use (e.g. nicotine or alcohol use) * Moderate or Severe Nicotine Dependence * Current alcohol use disorder * Illicit substance use other than marijuana use in the past year * Marijuana use more than 10 times in the past year * Major neurological or medical illness - Significant head trauma - Current use of medication affecting the central nervous system * MRI contraindications (e.g. irremovable metal on the body or pregnancy)
Contact & Investigator
Frequently Asked Questions
Who can join the NCT04281979 clinical trial?
This trial is open to participants of all sexes, aged 21 Years or older, up to 40 Years, studying Smoking. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT04281979 currently recruiting?
Yes, NCT04281979 is actively recruiting participants. Contact the research team at moralean@ohsu.edu for enrollment information.
Where is the NCT04281979 trial being conducted?
This trial is being conducted at Portland, United States.
Who is sponsoring the NCT04281979 clinical trial?
NCT04281979 is sponsored by Oregon Health and Science University. The trial plans to enroll 60 participants.