NCT07219498 Effects of a 5-Week Probiotic Supplementation Intervention on Markers of Delayed Onset Muscle Soreness
| NCT ID | NCT07219498 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University of Minnesota |
| Condition | Exercise Induced Muscle Damage |
| Study Type | INTERVENTIONAL |
| Enrollment | 24 participants |
| Start Date | 2026-02-05 |
| Primary Completion | 2026-12-31 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 24 participants in total. It began in 2026-02-05 with a primary completion date of 2026-12-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The purpose of this study is to evaluate how probiotic supplementation (PS) influences post-exercise recovery in healthy, physically active young adults. Researchers aim to determine if the Lactobacillus casei probiotic strain reduces symptoms of delayed onset muscle soreness (DOMS) based on perceived muscle soreness, pressure pain threshold, and power output following exercise induced muscle damage (EIMD).
Eligibility Criteria
Inclusion Criteria: * complete a minimum of 150 minutes a week of at least moderate intensity exercise in either an endurance-based or resistance-based training style based on a self-reported physical activity over the past month * good general health with no injuries or health conditions that would affect physical activity * willing to abstain from consistent NSAID use and other probiotic supplements over the course of this study Exclusion Criteria: * known musculoskeletal injuries or physical limitations that could interfere with performing the designated physical activity required * underlying conditions that could place them at an increased risk during exercise such as cardiovascular, respiratory, or metabolic diseases * currently take a probiotic supplement, are prescribed and taking an antibiotic during the intervention, or report using NSAIDs or steroids within the recovery time window * report using an NSAID more than twice a week on a regular basis
Contact & Investigator
Mary Stenson
PRINCIPAL INVESTIGATOR
University of Minnesota
Frequently Asked Questions
Who can join the NCT07219498 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 30 Years, studying Exercise Induced Muscle Damage. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07219498 currently recruiting?
Yes, NCT07219498 is actively recruiting participants. Contact the research team at fisc0887@d.umn.edu for enrollment information.
Where is the NCT07219498 trial being conducted?
This trial is being conducted at Minneapolis, United States.
Who is sponsoring the NCT07219498 clinical trial?
NCT07219498 is sponsored by University of Minnesota. The principal investigator is Mary Stenson at University of Minnesota. The trial plans to enroll 24 participants.