NCT07451600 Effectiveness of TMS on Spasticity and Balance for Patients With MS
| NCT ID | NCT07451600 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Ankara Etlik City Hospital |
| Condition | Multiple Sclerosis |
| Study Type | INTERVENTIONAL |
| Enrollment | 24 participants |
| Start Date | 2026-03-01 |
| Primary Completion | 2026-10-31 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 24 participants in total. It began in 2026-03-01 with a primary completion date of 2026-10-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Recently, non-invasive brain stimulation modalities such as transcranial magnetic stimulation (rTMS) and transcranial direct current stimulation have become treatment options. Among these methods, rTMS is a non-invasive brain stimulation technique that can affect descending corticospinal pathways, thereby modulating cortical excitability in the motor area where it is applied. This study will examine the effect of rTMS application on spasticity and balance in patients with multiple sclerosis. In addition, the indirect effects of the applications on gait pattern, joint range of motion, and pain will be evaluated.
Eligibility Criteria
Inclusion Criteria: * Being between the ages of 18 and 60 * Having been diagnosed with multiple sclerosis for more than six months * Having spasticity levels between 1 and 3 on the Modified Ashworth Scale (MAS) in the evaluated extremity * Having an EDSS SCORE between 0 and 6.5 * Voluntarily participating in the study Exclusion Criteria: * Poor general health (heart failure, COPD, etc.) * Presence of wound lesions on the skin * Presence of metal implants in the body * Pregnancy * Presence of a severe infection * Diagnosis of malignancy * Presence of a bleeding disorder * Use of a pacemaker * Presence of cardiac rhythm disorder * Presence of neurological disease other than multiple sclerosis * History of epilepsy * History of alcohol use * Change in medication within the last 6 months * Refusal to participate in the study
Contact & Investigator
Özgür Zeliha Karaahmet, professor
STUDY DIRECTOR
Ankara Etlik City Hospital
Frequently Asked Questions
Who can join the NCT07451600 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 60 Years, studying Multiple Sclerosis. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07451600 currently recruiting?
Yes, NCT07451600 is actively recruiting participants. Contact the research team at melike9671@gmail.com for enrollment information.
Where is the NCT07451600 trial being conducted?
This trial is being conducted at Ankara, Turkey (Türkiye).
Who is sponsoring the NCT07451600 clinical trial?
NCT07451600 is sponsored by Ankara Etlik City Hospital. The principal investigator is Özgür Zeliha Karaahmet, professor at Ankara Etlik City Hospital. The trial plans to enroll 24 participants.
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