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Recruiting Phase 3 NCT06904287

NCT06904287 Effectiveness of Magnesium in Addition to Prochlorperazine for the Treatment of Migraines

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Clinical Trial Summary
NCT ID NCT06904287
Status Recruiting
Phase Phase 3
Sponsor Wake Forest University Health Sciences
Condition Migraine
Study Type INTERVENTIONAL
Enrollment 100 participants
Start Date 2025-12-16
Primary Completion 2027-06

Trial Parameters

Condition Migraine
Sponsor Wake Forest University Health Sciences
Study Type INTERVENTIONAL
Phase Phase 3
Enrollment 100
Sex ALL
Min Age 18 Years
Max Age N/A
Start Date 2025-12-16
Completion 2027-06
Interventions
MagnesiumPlacebo

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Brief Summary

The purpose of this research study is to find out if using magnesium in addition to prochlorperazine will help reduce your migraine pain.

Eligibility Criteria

Inclusion Criteria: * Age ≥ 18 years or older * Able to provide informed consent * English speaking * Primary diagnosis of migraine. Patient with a previous diagnosis of migraine, who experience headaches with typical migraine features (e.g at least 2-3 of the following: recurrent, unilateral, pounding or throbbing in nature, associated with nausea), AND with a clinical exclusion of migraine mimics Exclusion Criteria: * Pregnancy defined as a positive urine HCG * Allergy or sensitivity to study drug * Stated history of renal insufficiency * Documented history of myasthenia gravis * Consumption of study drug within 48 hours prior to enrollment * Previously enrolled in this trial during a different patient encounter

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