NCT07613021 Effectiveness of Inspiratory Muscle Training in Weaning ICU Patients
| NCT ID | NCT07613021 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University of West Attica |
| Condition | Mechanically Ventilated ICU Patients |
| Study Type | INTERVENTIONAL |
| Enrollment | 45 participants |
| Start Date | 2026-04 |
| Primary Completion | 2029-06 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 45 participants in total. It began in 2026-04 with a primary completion date of 2029-06.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Patients in critical condition, due to their prolonged stay in the Intensive Care Unit (ICU), the severity of the underlying disease, and potential adverse effects of hospitalization, may develop serious complications, such as muscle atrophy and weakness, which also affect the respiratory muscles. It is characteristic that within the first 18-69 hours of mechanical ventilation (MV), proteolytic processes occur that lead to rapid atrophy of the diaphragm. Diaphragmatic dysfunction acquired during the ICU stay thus appears to have an adverse effect on weaning from mechanical ventilation, length of ICU stay, length of hospital stay, functional status, quality of life, and mortality within the ICU and the hospital. Inspiratory muscle training (IMT) has been identified as an intervention that could augment weaning, preventing the dedtrimental effects of MV. The purpose of this study is to assess the effect of an IMT protocol in weaning success of ICU patients. Specifically, an electronic device will be used that incorporates a tapered flow resistive technique.
Eligibility Criteria
Inclusion Criteria: * ≥ 72h invasive mechanical ventilation * adequate co-operativeness as assessed by 5SQ ≥ 3. Exclusion Criteria: * terminal condition or palliative care * neuromuscular or neurological conditions prior to ICU admission
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07613021 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Mechanically Ventilated ICU Patients. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07613021 currently recruiting?
Yes, NCT07613021 is actively recruiting participants. Contact the research team at ipatsaki@uniwa.gr for enrollment information.
Where is the NCT07613021 trial being conducted?
This trial is being conducted at Chalcis, Greece, Nikaia, Greece.
Who is sponsoring the NCT07613021 clinical trial?
NCT07613021 is sponsored by University of West Attica. The trial plans to enroll 45 participants.