NCT07001449 Effectiveness of Communication-Focused Pain Neuroscience Education in Chronic Musculoskeletal Pain
| NCT ID | NCT07001449 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University of Thessaly |
| Condition | Chronic Musculoskeletal Pain |
| Study Type | INTERVENTIONAL |
| Enrollment | 90 participants |
| Start Date | 2025-06-17 |
| Primary Completion | 2026-08-30 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 90 participants in total. It began in 2025-06-17 with a primary completion date of 2026-08-30.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This randomized controlled trial aims to evaluate the effectiveness of the "Algo(S)Therapy" Pain Neuroscience Education (PNE) program in patients with chronic musculoskeletal pain. The study will assess whether the integration of communication skills training for physiotherapists enhances the outcomes of PNE. Participants will be randomly assigned to one of three groups: (1) PNE with communication-focused delivery, (2) PNE without communication emphasis, or (3) standard- usual physiotherapy care. The primary objective is to determine whether PNE combined with enhanced communication skills leads to greater improvements in pain, function, and psychosocial outcomes compared to the other interventions.
Eligibility Criteria
Inclusion Criteria: * Adults aged 18 to 65 years * Diagnosis of chronic musculoskeletal pain in the lumbar spine, cervical spine, shoulder, or knee * Pain duration longer than 3 months * Pain intensity ≥3/10 on the Numeric Pain Rating Scale (NPRS) * Pain present most days of the week * Able to understand and speak the Greek language Exclusion Criteria: * Acute pain in any body region * Neurological disorders or myopathies * Chronic pain of non-musculoskeletal origin * Active cancer diagnosis * History of trauma, fractures, or surgery in the past year * Pregnancy * Diagnosis of fibromyalgia * Cognitive impairments affecting communication or completion of questionnaires * Current use of corticosteroid medication * Participation in other treatment programs or alternative therapies during the study period * Concurrent enrollment in another clinical trial
Contact & Investigator
Eleni Kapreli, Professor
STUDY CHAIR
Physiotherapy Department, University of Thessaly, Greece
Frequently Asked Questions
Who can join the NCT07001449 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 65 Years, studying Chronic Musculoskeletal Pain. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07001449 currently recruiting?
Yes, NCT07001449 is actively recruiting participants. Contact the research team at ksavvoulidou@uth.gr for enrollment information.
Where is the NCT07001449 trial being conducted?
This trial is being conducted at Lamia, Greece.
Who is sponsoring the NCT07001449 clinical trial?
NCT07001449 is sponsored by University of Thessaly. The principal investigator is Eleni Kapreli, Professor at Physiotherapy Department, University of Thessaly, Greece. The trial plans to enroll 90 participants.