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Recruiting Phase 2 NCT06665594

NCT06665594 Effect of TXA on Reducing Bruising After Filler Injection

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Clinical Trial Summary
NCT ID NCT06665594
Status Recruiting
Phase Phase 2
Sponsor University of Wisconsin, Madison
Condition Facial Filler Injections
Study Type INTERVENTIONAL
Enrollment 40 participants
Start Date 2025-12-05
Primary Completion 2026-11

Trial Parameters

Condition Facial Filler Injections
Sponsor University of Wisconsin, Madison
Study Type INTERVENTIONAL
Phase Phase 2
Enrollment 40
Sex ALL
Min Age 18 Years
Max Age 89 Years
Start Date 2025-12-05
Completion 2026-11
Interventions
Hyaluronic Acid (HA)Tranexamic Acid (TXA)Saline (placebo)

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Brief Summary

The goal of this clinical trial is to look at the effect tranexamic acid (TXA) may have on reducing bruising, swelling, and pain after facial filler injection. The main question it aims to answer is: * Does the addition of TXA to hyaluronic acid (HA) reduce bruising, swelling, and tenderness after HA injection? Participants will receive the study medication along with the standard facial filler injection and complete surveys.

Eligibility Criteria

Inclusion Criteria: * Age equal to or greater than 18 but less than or equal to 89 years. * Participants interested in facial filler (HA) injection. * English speaking. Exclusion Criteria: * Minors or under the age of 18 * Participant over the age of 89 * Pregnant or breast-feeding women * Individuals unable to give consent due to another condition such as impaired decision-making capacity. * Individuals with a history of a thrombotic event (DVT, PE, stroke, MI) or genetic disorder that increases risk of thrombosis * Participants undergoing unilateral facial filler (HA) injection * Participants with history of hypersensitivity to TXA or any of the other ingredients * Participants that are on current therapeutic anticoagulation therapy and aspirin use * Participants with stage 2 or greater renal failure * Participants on hemodialysis or peritoneal dialysis * History of diabetes or seizures * Current tobacco smokers * Acquired defective color vision

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