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Recruiting NCT06236503

NCT06236503 Effect of Transcranial Direct Current Stimulation in Altered States of Consciousness

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Clinical Trial Summary
NCT ID NCT06236503
Status Recruiting
Phase
Sponsor IRCCS Centro Neurolesi Bonino Pulejo
Condition Neurologic Disorder
Study Type INTERVENTIONAL
Enrollment 100 participants
Start Date 2023-01-10
Primary Completion 2025-12-20

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age 75 Years
Study Type INTERVENTIONAL
Interventions
Real StimulationPlacebo Stimulation

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

This trial targets 100 participants in total. It began in 2023-01-10 with a primary completion date of 2025-12-20.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

Transcranial Direct Current Stimulation (tDCS) is a non-invasive, painless brain stimulation treatment that uses low-intensity direct electrical currents to stimulate specific parts of the brain. Transcranial Direct Current Stimulation (tDCS) can both facilitate anodic stimulation and inhibit cathodic stimulation specific brain areas since many neurological and psychiatric disorders are connected to hypoactivity or hyperactivity in specific areas of the nervous system. This phenomenon is based on two processes: the reorganization of functional neural circuits and their reconstruction. In light of the studies mentioned above, it is presumed that Transcranial Direct Current Stimulation (tDCS) can be a valuable tool to facilitate the process of neuroplasticity in individuals with chronic neurological diseases and in patients with impaired consciousness following severe brain injury. A previous study demonstrated that a single session of transcranial direct current electrical stimulation could temporarily improve signs of consciousness in patients in a minimally conscious state (MCS)

Eligibility Criteria

Inclusion Criteria: * Patients diagnosed with a minimally conscious state will be evaluated and stimulated, provided that written informed consent is obtained from a family member. Exclusion Criteria: patients in coma patients with metallic brain implants, craniotomy or pacemaker

Frequently Asked Questions

Who can join the NCT06236503 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, up to 75 Years, studying Neurologic Disorder. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT06236503 currently recruiting?

Yes, NCT06236503 is actively recruiting participants. Visit ClinicalTrials.gov or contact IRCCS Centro Neurolesi Bonino Pulejo to inquire about joining.

Where is the NCT06236503 trial being conducted?

This trial is being conducted at Messina, Italy.

Who is sponsoring the NCT06236503 clinical trial?

NCT06236503 is sponsored by IRCCS Centro Neurolesi Bonino Pulejo. The trial plans to enroll 100 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: July 2026  ·  Data Methodology