NCT06229002 Effect of Transcranial Alternative Current Stimulation at Alpha Frequency (α-tACS) on Stressed Healthy Subjects
| NCT ID | NCT06229002 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Hôpital le Vinatier |
| Condition | Healthy |
| Study Type | INTERVENTIONAL |
| Enrollment | 40 participants |
| Start Date | 2024-01-24 |
| Primary Completion | 2027-02-01 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 40 participants in total. It began in 2024-01-24 with a primary completion date of 2027-02-01.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
stress. Notably, several studies reported that stress could alter impulsivity, source monitoring, and time perception. Several mechanisms are involved in the response to a stress factor, among them the hypothalamic-pituitary-adrenal (HPA) axis. The cortisol reactivity (it means the cortisol secretion after the exposure to a standardized stress factor) is a reliable tool to assess the function of HPA. Cortisol secretion is bidirectionally influenced by the prefrontal cortex (PFC), which is involved in the expression and regulation of stress as well. The asymmetry of the alpha band (AFα) is a well known electrophysiological parameter to assess the function of PFC. More precisely, AFα is arising a growing interest, as it is believed to be correlated with the cortisol reactivity. Modifying this asymmetry could influence the stress response. Transcranial Alternating Current Stimulation (tACS) consists in delivering a sinusoidal alternating current between two electrodes placed on the scalp at a predefined frequency. Previous studious reported that tACS, if delivered at the alpha frequency, increased the alpha band in the stimulated areas
Eligibility Criteria
Inclusion Criteria: * Right-handed Men and Women aged between 18 and 45 * If woman, hormonal contraception required * Having given their written informed consent * Affiliated with a social security scheme * French speakers and readers Exclusion Criteria: * Contraindication to the exposure to exposure to tACS * Current psychiatric disorder as classified in the DSM-5 * Regular intake of any psychotropic drug or Beta Blocker * Recent exposure to a traumatic event * Any debilitating condition making the experimental procedure not feasible * Pregnancy
Frequently Asked Questions
Who can join the NCT06229002 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 45 Years, studying Healthy. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06229002 currently recruiting?
Yes, NCT06229002 is actively recruiting participants. Visit ClinicalTrials.gov or contact Hôpital le Vinatier to inquire about joining.
Where is the NCT06229002 trial being conducted?
This trial is being conducted at Bron, France.
Who is sponsoring the NCT06229002 clinical trial?
NCT06229002 is sponsored by Hôpital le Vinatier. The trial plans to enroll 40 participants.