NCT06981767 Effect of Topical Bromelain Versus Topical Corticosteroids in the Management of Oral Lichen Planus
| NCT ID | NCT06981767 |
| Status | Recruiting |
| Phase | Phase 2 |
| Sponsor | Cairo University |
| Condition | Oral Lichen Planus |
| Study Type | INTERVENTIONAL |
| Enrollment | 42 participants |
| Start Date | 2026-02-18 |
| Primary Completion | 2026-05-15 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
In Phase 2, researchers evaluate early signs of effectiveness. You may be randomized to receive the active treatment or a comparator. Monitoring continues closely.
This trial targets 42 participants in total. It began in 2026-02-18 with a primary completion date of 2026-05-15.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Bromelain, an enzyme extract derived from pineapples, has shown promise due to its anti-inflammatory and wound-healing properties. However, its efficacy in treating oral mucosal ulcers remains unexplored. This study aims to provide clinical evidence on the efficacy of bromelain for managing OLP, potentially offering a safer and more effective treatment option.
Eligibility Criteria
Inclusion Criteria: * Patients suffering from symptomatic OLP * Patients free from any visible oral lesions other than OLP. * Patients who agreed to take the supplied interventions. * Patient who will agree to participate in the study. * Patients who will accept to sign the informed consent. Exclusion Criteria: * Patients suffering from any systemic disease. * Treatment with any systemic treatment such as systemic steroids, other immunosuppressive drugs or non-steroidal anti-inflammatory drugs at least eight weeks. * Treatment with any oral topical medications for at least four weeks prior to the study. * Pregnant and lactating mothers.
Frequently Asked Questions
Who can join the NCT06981767 clinical trial?
This trial is open to participants of all sexes, studying Oral Lichen Planus. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
What phase is the NCT06981767 trial and what does that mean for participants?
Phase 2 trials evaluate whether the treatment shows signs of effectiveness while continuing to monitor safety. More participants are enrolled than in Phase 1 to help refine the treatment protocol.
Is NCT06981767 currently recruiting?
Yes, NCT06981767 is actively recruiting participants. Visit ClinicalTrials.gov or contact Cairo University to inquire about joining.
Where is the NCT06981767 trial being conducted?
This trial is being conducted at Cairo, Egypt.
Who is sponsoring the NCT06981767 clinical trial?
NCT06981767 is sponsored by Cairo University. The trial plans to enroll 42 participants.