NCT06797752 Effect of the Stellate Ganglion Block on the Retinal Microcirculation
| NCT ID | NCT06797752 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University of Texas Southwestern Medical Center |
| Condition | OCTA |
| Study Type | OBSERVATIONAL |
| Enrollment | 50 participants |
| Start Date | 2024-10-07 |
| Primary Completion | 2026-10-07 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 50 participants in total. It began in 2024-10-07 with a primary completion date of 2026-10-07.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Surges in the sympathetic nervous system occur at the ictus of a variety of neurological critical illnesses including intracranial hemorrhage and ischemic stroke. It is hypothesized that these exaggerated increases in sympathetic nervous activity produce maladaptations that promote secondary brain injury. One of these possible mechanisms include diffuse vasospasm that cause cerebral ischemia. Hence, methods to abrogate the sympathetic nervous system in this context are under active investigation. One possible method is the regional anesthesia technique of the stellate ganglion nerve block, which is ordinarily used for complex regional pain syndrome, but has been shown to reduce cerebral sympathetic activity and reduces vasospasm in patients with subarachnoid hemorrhage. However, its effect on the microcirculation is not clear. Hence, we propose to study patients receiving the stellate ganglion nerve block as part of their standard medical care and to image their retinal microcirculation before and after the procedure using Optical Coherence Tomography Angiography (OCTA).
Eligibility Criteria
Inclusion Criteria: * Age 18 years or older * Patients receiving the stellate ganglion nerve block for an approved indication, e.g. complex regional pain syndrome Exclusion Criteria: * Pregnancy * Non-English speaking * Temporary or permanent physical limitation that renders the patient unable to sit up and look inside OCTA device
Contact & Investigator
Noah Jouett, DO, PhD
PRINCIPAL INVESTIGATOR
University of Texas Southwestern Medical Center
Frequently Asked Questions
Who can join the NCT06797752 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying OCTA. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06797752 currently recruiting?
Yes, NCT06797752 is actively recruiting participants. Contact the research team at noah.jouett@utsouthwestern.edu for enrollment information.
Where is the NCT06797752 trial being conducted?
This trial is being conducted at Dallas, United States.
Who is sponsoring the NCT06797752 clinical trial?
NCT06797752 is sponsored by University of Texas Southwestern Medical Center. The principal investigator is Noah Jouett, DO, PhD at University of Texas Southwestern Medical Center. The trial plans to enroll 50 participants.