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Recruiting NCT07449117

NCT07449117 Effect of Striatal Temporal Interference Stimulation on Language Processing in Neurodegenerative Diseases

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Clinical Trial Summary
NCT ID NCT07449117
Status Recruiting
Phase
Sponsor Masaryk University
Condition Mild Cognitive Impairment (MCI) Amnestic
Study Type INTERVENTIONAL
Enrollment 70 participants
Start Date 2026-03
Primary Completion 2027-12

Eligibility & Interventions

Sex All sexes
Min Age 60 Years
Max Age 80 Years
Study Type INTERVENTIONAL
Interventions
Active Temporal Interference Stimulation (TIS)Placebo / Sham TIS

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

This trial targets 70 participants in total. It began in 2026-03 with a primary completion date of 2027-12.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

The purpose of this study is to investigate the immediate effects of non-invasive temporal interference stimulation (TIS) targeting the striatum on sentence processing and brain connectivity in patients with neurodegenerative diseases.

Eligibility Criteria

Inclusion Criteria: * Possible or probable Mild Cognitive Impairment with Lewy Bodies (MCI-LB), in Parkinson's Disease (MCI-PD) or Amnestic Mild Cognitive Impairment (aMCI). Exclusion Criteria: * Any severe psychiatric disorder. * History of other neurological diseases affecting the central nervous system. * Severe head trauma. * Uncompensated internal or oncological disease. * Presence of MRI-incompatible metal in the body (e.g., pacemaker).

Contact & Investigator

Central Contact

Ľubomíra Nováková, Ph.D.

✉ lubomira.novakova@ceitec.muni.cz

📞 +420 549 497 766

Frequently Asked Questions

Who can join the NCT07449117 clinical trial?

This trial is open to participants of all sexes, aged 60 Years or older, up to 80 Years, studying Mild Cognitive Impairment (MCI) Amnestic. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT07449117 currently recruiting?

Yes, NCT07449117 is actively recruiting participants. Contact the research team at lubomira.novakova@ceitec.muni.cz for enrollment information.

Where is the NCT07449117 trial being conducted?

This trial is being conducted at Brno, Czechia.

Who is sponsoring the NCT07449117 clinical trial?

NCT07449117 is sponsored by Masaryk University. The trial plans to enroll 70 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: September 2026  ·  Data Methodology