NCT07091981 Effect of Rotary File Number on MB2 Canal Negotiation and Postoperative Pain
| NCT ID | NCT07091981 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Mehmet Adıgüzel |
| Condition | Postoperative Pain |
| Study Type | INTERVENTIONAL |
| Enrollment | 152 participants |
| Start Date | 2025-06-18 |
| Primary Completion | 2025-09-01 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 152 participants in total. It began in 2025-06-18 with a primary completion date of 2025-09-01.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This randomized controlled clinical trial aims to evaluate the effect of the number of rotary files on working length negotiation and postoperative pain in the second mesiobuccal (MB2) canals of maxillary first molars. Patients are assigned to one of four groups according to the number of rotary files used: single-, two-, three-, or four-file systems. Postoperative pain is assessed on each of the seven consecutive postoperative days (Days 1-7) using a visual analog scale (VAS), and working length negotiation success is recorded during canal instrumentation.
Eligibility Criteria
Inclusion Criteria: * Systemically healthy individuals aged between 20 and 65 years * Requiring primary endodontic treatment of maxillary first molars * Diagnosis of asymptomatic apical periodontitis and pulp necrosis based on clinical and radiographic findings * Presence of a second mesiobuccal (MB2) canal in the maxillary first molar * Absence of or only minimal preoperative pain or symptoms * Periapical lesions smaller than 5 mm in diameter * Ability to comply with follow-up visits and effectively communicate during the treatment process Exclusion Criteria: * Presence of symptomatic apical periodontitis or acute apical abscess * Retreatment cases (teeth previously treated endodontically) * Use of medications such as narcotics, antibiotics, sedatives, or antidepressants within one week prior to treatment * Presence of a sinus tract, periapical abscess, or facial cellulitis * Pregnancy or breastfeeding * Inability to understand or follow the study instructions
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07091981 clinical trial?
This trial is open to participants of all sexes, aged 20 Years or older, up to 65 Years, studying Postoperative Pain. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07091981 currently recruiting?
Yes, NCT07091981 is actively recruiting participants. Contact the research team at dt.mehmetadiguzel@gmail.com for enrollment information.
Where is the NCT07091981 trial being conducted?
This trial is being conducted at Antakya, Turkey (Türkiye).
Who is sponsoring the NCT07091981 clinical trial?
NCT07091981 is sponsored by Mehmet Adıgüzel. The trial plans to enroll 152 participants.