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Recruiting NCT06426173

Effect of Resistance Training in Patients on the Waiting List for Heart Transplant

Trial Parameters

Condition Heart Failure
Sponsor University of Sao Paulo General Hospital
Study Type INTERVENTIONAL
Phase N/A
Enrollment 50
Sex ALL
Min Age 18 Years
Max Age 70 Years
Start Date 2024-06-18
Completion 2025-03-18
Interventions
Resistance Training ProgramStandard Treatment Group

Brief Summary

The present longitudinal, randomized, and blinded clinical trial aims to: * Evaluate the effects of resistance training on the functional capacity, quality of life, and cardiac biomarkers of hospitalized patients with heart failure (HF) on the waiting list for heart transplantation (HTx). * Evaluate the associations between Fried's frailty classification and functional capacity responses to resistance training. The protocol will have a total duration of 12 weeks.

Eligibility Criteria

Inclusion Criteria: * patients included in heart transplant list ≤1 month * hemodynamically stable in the last 48 hours defined as mean arterial pressure (MAP) ≥ 60 mmHg and ≤ 120 mmHg and - Heart rate (HR) ≥ 60 bpm and ≤ 120 mmHg. * dobutamine dose ≤ 10 mcg/kg/min Exclusion Criteria: * heart failure of arrhythmogenic and/or restrictive etiology * presence of uncontrolled acute arrhythmias * cognitive, orthopedic, or neuromotor changes that prevent functional tests from being carried out

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