Effect of Remote Local Peripheral Nerve Cooling on Pain of Arterial Puncture
Trial Parameters
Brief Summary
In this project, volunteers will be recruited to cool the superficial skin of the axillary brachial plexus away from the puncture point, resulting in local peripheral nerve cooling, and observe its impact on the pain of arterial puncture.To explore the local peripheral nerve cooling treatment can produce controllable and reversible analgesic effect even if away from the wound, and provide a new nonpharmaceutical analgesic mode for clinical.
Eligibility Criteria
Inclusion Criteria: 1. 18 \~ 65 years old; 2. ASA I-II level; 3. Patients with perioperative invasive arterial blood pressure monitoring; 4. Right-handed; 5. Allen test was normal (palm color quickly turned red or returned to normal within 10 seconds after release of ulnar artery pressure); 6. Participate voluntarily and be able to understand and sign informed consent. Exclusion Criteria: 1. Patients with a history of musculoskeletal, vascular, neurological or psychiatric disorders; 2. Patients with a history of diabetes or other systemic diseases 3. Patients who used any analgesic medication within the month before and during the study; 4. Patients with a history of smoking, alcohol or drug addiction; 5. Paraesthesia, scar, redness, damage, rash, etc. exist in the skin of the patient in the test area; 6. Patients whose surgical area overlaps with the cooling treatment or puncture area; 7. Female subjects are menstruating.