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Recruiting NCT05838508

Effect of Physical Activity Pattern on Cardiometabolic Health

Trial Parameters

Condition Life Style
Sponsor Brigham and Women's Hospital
Study Type INTERVENTIONAL
Phase N/A
Enrollment 26
Sex ALL
Min Age 18 Years
Max Age 45 Years
Start Date 2024-10-11
Completion 2026-08-30
Interventions
Exercise intervention

Brief Summary

The goal of this study is to understand the interaction between the circadian system and physical activity. Participants will: * complete 2 inpatient stays * perform moderate exercise * be provided with identical meals * have frequent blood draws * provide urine and saliva samples

Eligibility Criteria

Inclusion Criteria: * 18-45 yr old * Body mass index (BMI) 18.5 - 34.9 kg/m2 * No acute, chronic or debilitating medical conditions (e.g. metabolic, cardiovascular, respiratory, neurological, cancers, etc.) * Willing to adhere to the protocol requirements for the duration of the study Exclusion Criteria: * Currently smoking/vaping or 5 or more years of smoking/vaping * Currently pregnant or breastfeeding * History of drug or alcohol dependency * History of psychiatric illness or disorder * Any hospitalization due to COVID-19 * Inability to exercise for any reason * Any known contraindication to exercise testing based on current ACSM guidelines

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