NCT05424302 Effect of Peripheral Vestibular Disease Location on Outcomes Following Home-based Virtual Reality Vestibular Therapy
| NCT ID | NCT05424302 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University of British Columbia |
| Condition | Peripheral Vestibular Disorder |
| Study Type | INTERVENTIONAL |
| Enrollment | 50 participants |
| Start Date | 2024-06-01 |
| Primary Completion | 2025-09 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 50 participants in total. It began in 2024-06-01 with a primary completion date of 2025-09.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This parallel-group randomized controlled trial aims to determine if the location of the lesion(s) in the vestibular system (unilateral versus bilateral, lateral semi-circular canal versus otolith) impacts the effectiveness of adjunct take-home head-mounted display (HMD) virtual reality (VR) therapy in improving patient symptomatology. Fifty patients meeting inclusion criteria will be recruited from the principal investigator's neurotology clinic. Baseline symptomatology questionnaires will be completed, followed by random allocation to virtual reality and control groups. Vestibular rehabilitation and virtual reality protocols will be adhered to for 4 to 8 weeks, followed by symptomatology questionnaires. Data analysis will be conducted to answer the study's objectives.
Eligibility Criteria
Inclusion Criteria: * Participants diagnosed with chronic (≥3 months) unilateral or bilateral peripheral vestibular disorders such as vestibular neuritis, labyrinthitis, Ramsay Hunt syndrome, ischemic lesion and trauma. * Diagnosis made using caloric testing (≥25% reduced vestibular response) and either ocular vestibular evoked myogenic potential (oVEMP) or cervical vestibular evoked myogenic potential (cVEMP) testing. * Participants prescribed vestibular rehabilitation * Participants ≥18 years of age * Access to an android or iOS smart phone Exclusion Criteria: * Pregnant participants * Participant diagnosed with a central vestibular disorder
Contact & Investigator
Desmond A Nunez, MD, MBA
PRINCIPAL INVESTIGATOR
Division of Otolaryngology, Department of Surgery, The University of British Columbia
Frequently Asked Questions
Who can join the NCT05424302 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Peripheral Vestibular Disorder. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT05424302 currently recruiting?
Yes, NCT05424302 is actively recruiting participants. Contact the research team at aheff12@student.ubc.ca for enrollment information.
Where is the NCT05424302 trial being conducted?
This trial is being conducted at Vancouver, Canada.
Who is sponsoring the NCT05424302 clinical trial?
NCT05424302 is sponsored by University of British Columbia. The principal investigator is Desmond A Nunez, MD, MBA at Division of Otolaryngology, Department of Surgery, The University of British Columbia. The trial plans to enroll 50 participants.