Effect of Ketalar or Dexmedetomidine on Increased Sensitivity to Pain Following Treatment With Remifentanil
Trial Parameters
Brief Summary
Analgesia is one of the pillars of anesthesia. One of the common opiates for pain relief, with a short half-life, is Remifentanil. However, following Remifentanil treatment an increased sensitivity to pain \[hyperalgesia\] appears. The aim of the study is to compare the effects between complementary treatments, like Ketalar and Dexmedetomidine, in preventing increased sensitivity to pain after Remifentanil treatment
Eligibility Criteria
Inclusion Criteria: • Patients who are about to undergo alaparoscopic cholecystectomy under general anesthesia Exclusion Criteria: * Patients with sensitivity to the anesthetic * Patients with chronic pain who are in regular treatment * Urgent surgery * Patients with ischemic heart disease * Patients with known bradycardia * Patients with a pacemaker * Prolonged use of opiates * Kidney/liver function problems