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Recruiting Phase 4 NCT07333859
Effect of IV Lidocaine on Duodenal Peristalsis and Sedation in ERCP
Trial Parameters
Condition Duodenal Spasm
Sponsor Ankara City Hospital Bilkent
Study Type INTERVENTIONAL
Phase Phase 4
Enrollment 120
Sex ALL
Min Age 18 Years
Max Age 85 Years
Start Date 2026-02-11
Completion 2026-02-11
All Conditions
Interventions
Lidocaine Hydrochloride 2%0.9 % Normal Saline
Brief Summary
This study aims to evaluate the efficacy of intravenous lidocaine infusion on duodenal peristalsis during Endoscopic Retrograde Cholangiopancreatography (ERCP). The study compares lidocaine against a placebo to determine if lidocaine can reduce the need for rescue spasmolytics (hyoscine-N-butylbromide or glucagon), decrease propofol consumption, and improve hemodynamic stability.
Eligibility Criteria
Inclusion Criteria: * Patients scheduled for elective ERCP. ASA Physical Status I, II, or III. Age between 18 and 85 years. Provided written informed consent. Exclusion Criteria: * Allergy to amide-type local anesthetics. Severe hepatic or renal failure. History of AV block or severe cardiac arrhythmia. Pregnancy or lactation. Chronic opioid use. Patient refusal.