Trial Parameters
Brief Summary
Attention Deficit/Hyperactivity Disorder (ADHD) is a common neurodevelopmental disorder characterized by persistent symptoms of attention deficit and/or hyperactivity/impulsivity . Currently, the first line drugs for treating ADHD are central stimulants such as Tomoxetine and Guanfaxine. However, there is a risk of drug abuse and misuse, which often affects sleep and appetite, only 50% of patients can fully tolerate. This project uses the iTBS stimulation on weekends, children with ADHD finish scale evaluation, magnetic resonance imaging analysis, and cognitive function before and after stimulation, This study explores its therapeutic effect on attention deficit in children and adolescents with ADHD.
Eligibility Criteria
Inclusion Criteria: * Clinical diagnosis of ADHD in accordance with DSM-V; * Age 6-12 years old, regardless of gender * Right-handed * Han nationality or born in the Han nationality Ghetto * The course of the disease is greater than 6 months * Webster children's intelligence ≥ 70 * The patient's guardian agrees and signs an informed consent form. Exclusion Criteria: * Concomitant mental disorders such as anxiety and depression; * Widespread developmental disorders and other neurological developmental related disorders; * Complication with other important organ diseases such as heart and lungs; * Suffering from diseases such as epilepsy and tic disorder; * Individuals who cannot tolerate rTMS treatment or cannot cooperate with treatment. * Patients taking psychoactive drugs, antipsychotics, antidepressants, or mood stabilizers 3 months prior to enrollment or during rTMS treatment; In addition to the minimum effective therapeutic dose of Tomoxetine (1.2-1.4 mg • kg/day), there has been s