NCT07523854 Effect of Graft Type on Knee Muscle Strength After ACL Reconstruction
| NCT ID | NCT07523854 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Hacettepe University |
| Condition | Anterior Cruciate Ligament Reconstruction Rehabilitation |
| Study Type | OBSERVATIONAL |
| Enrollment | 80 participants |
| Start Date | 2026-01-23 |
| Primary Completion | 2027-01-25 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 80 participants in total. It began in 2026-01-23 with a primary completion date of 2027-01-25.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This prospective observational study will compare recovery after anterior cruciate ligament reconstruction using quadriceps tendon autograft or hamstring tendon autograft. The main goal is to examine differences in knee muscle strength recovery during the early and mid-term postoperative period. Participants aged 13 to 45 years who undergo unilateral ACL reconstruction and meet the eligibility criteria will be followed at Hacettepe University. Knee extensor and flexor strength will be assessed using isometric testing at postoperative weeks 4, 8, and 12 and month 6, and with isokinetic concentric testing at months 3 and 6. Functional outcomes and kinesiophobia will also be evaluated at month 6 using IKDC, KOOS, and the Tampa Scale for Kinesiophobia. All participants will receive the same standard postoperative rehabilitation program under physiotherapist supervision. The study aims to clarify whether graft type is associated with different patterns of muscle strength recovery and functional improvement after ACL reconstruction
Eligibility Criteria
Inclusion Criteria: * Age 13 to 45 years * Undergoing anterior cruciate ligament reconstruction with either hamstring tendon autograft or quadriceps tendon autograft * Unilateral anterior cruciate ligament injury * Complete ACL tear with accompanying minimal collateral ligament injury and first-degree meniscal tear * Tegner Activity Score of 5 or higher * Willingness to participate in the study Exclusion Criteria: * Anterior cruciate ligament reconstruction with patellar tendon autograft or allograft * Revision surgery * Systemic or neurological disease * Multiple ligament injuries * Grade III lateral or medial collateral ligament tear or significant articular cartilage lesion * Failure to regularly attend the rehabilitation program during the first 3 postoperative months * History of lower extremity injury in the contralateral limb within the last 12 months * Hypertension, cardiovascular disease, peripheral vascular disease, history of deep vein thrombosis, neurological disease, systemic inflammation, diabetes, cancer, or obesity
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07523854 clinical trial?
This trial is open to participants of all sexes, aged 13 Years or older, up to 45 Years, studying Anterior Cruciate Ligament Reconstruction Rehabilitation. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07523854 currently recruiting?
Yes, NCT07523854 is actively recruiting participants. Contact the research team at volgamel@yahoo.com for enrollment information.
Where is the NCT07523854 trial being conducted?
This trial is being conducted at Ankara, Turkey (Türkiye).
Who is sponsoring the NCT07523854 clinical trial?
NCT07523854 is sponsored by Hacettepe University. The trial plans to enroll 80 participants.