NCT07635576 Effect of Gastric Electrical Stimulation on Serum Insulin Levels
| NCT ID | NCT07635576 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Indiana University |
| Condition | Gastroparesis Nondiabetic |
| Study Type | INTERVENTIONAL |
| Enrollment | 32 participants |
| Start Date | 2026-07-23 |
| Primary Completion | 2028-07-31 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 32 participants in total. It began in 2026-07-23 with a primary completion date of 2028-07-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The goal of this observational study is to determine how much effect turning the subject's Gastric Electrical Stimulator off for up to four hours will have on levels of insulin, C-peptide, GLP-1 and Glucose levels in patients with gastroparesis who have had a GES for at least three months, who are not taking diabetic prescribed exogenous insulin. EKG recordings will be made and analyzed for Heart Rate Variability and Power Spectral Analysis.
Eligibility Criteria
Inclusion Criteria: * • At least 18 years of age. * Documented diagnosis of gastroparesis * Not taking diabetic prescribed exogenous insulin. * Patient has a GES device that has been implanted for at least 3 months. * Willing to give up to 8 blood samples. * Willing to lie in a bed for up to 5.5 hours. Exclusion Criteria: * • Pregnancy * History of allergic reaction to EKG lead placement adhesives. * Unable to give informed consent. * Unwilling to give up to 8 5 ml blood samples. * Unwilling to lie in a bed for up to 5.5 hours.
Contact & Investigator
Thomas V Nowak, MD
PRINCIPAL INVESTIGATOR
IU School of Medicine/IU Health
Frequently Asked Questions
Who can join the NCT07635576 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 70 Years, studying Gastroparesis Nondiabetic. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07635576 currently recruiting?
Yes, NCT07635576 is actively recruiting participants. Contact the research team at maschi@iu.edu for enrollment information.
Where is the NCT07635576 trial being conducted?
This trial is being conducted at Indianapolis, United States, Indianapolis, United States.
Who is sponsoring the NCT07635576 clinical trial?
NCT07635576 is sponsored by Indiana University. The principal investigator is Thomas V Nowak, MD at IU School of Medicine/IU Health. The trial plans to enroll 32 participants.