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Recruiting Phase 4 NCT07598214

NCT07598214 Effect of Diosmin/Hesperidin Combination on Platinum Compounds-Induced Nephropathy in Cancer Patients

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Clinical Trial Summary
NCT ID NCT07598214
Status Recruiting
Phase Phase 4
Sponsor Beni-Suef University
Condition Cancer Patients
Study Type INTERVENTIONAL
Enrollment 100 participants
Start Date 2025-02-03
Primary Completion 2026-11-03

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age 75 Years
Study Type INTERVENTIONAL
Interventions
diosmin/hesperdin

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

Phase 4 studies follow an already-approved treatment in real-world conditions to monitor long-term safety and effectiveness.

This trial targets 100 participants in total. It began in 2025-02-03 with a primary completion date of 2026-11-03.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

The current study aims to investigate the protective properties of diosmin/hesperidin on cisplatin-induced nephrotoxicity.

Eligibility Criteria

Inclusion Criteria: * Patients of 18 to 75 year-age must have histologically or cytologically confirmed cancer by the Laboratory of Pathology receiving a platinum compound chemotherapy. Exclusion Criteria: * -History of allergic reactions attributed to drugs in the study. * Pregnant women. * Life expectancy less than 6 months * Inability or unwillingness to comply with research protocols. * Cancer patients with impaired renal function (creatinine clearance \< 50 mL/min) * Preexisting hearing loss. * Patients taking nephrotoxic drugs; and those who have a history of allergic reactions to platinum-containing compounds.

Contact & Investigator

Central Contact

marwa mohsen, PhD

✉ marwa.mohsen@pharm.bsu.edu.eg

📞 01202203223

Principal Investigator

marwa mohsen

PRINCIPAL INVESTIGATOR

clinical pharmacy department, Beni Suef University

Frequently Asked Questions

Who can join the NCT07598214 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, up to 75 Years, studying Cancer Patients. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

What phase is the NCT07598214 trial and what does that mean for participants?

Phase 4 studies are conducted after a treatment has been approved. They monitor long-term safety and real-world effectiveness in a broader patient population.

Is NCT07598214 currently recruiting?

Yes, NCT07598214 is actively recruiting participants. Contact the research team at marwa.mohsen@pharm.bsu.edu.eg for enrollment information.

Where is the NCT07598214 trial being conducted?

This trial is being conducted at Banī Suwayf, Egypt.

Who is sponsoring the NCT07598214 clinical trial?

NCT07598214 is sponsored by Beni-Suef University. The principal investigator is marwa mohsen at clinical pharmacy department, Beni Suef University. The trial plans to enroll 100 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology