NCT07549373 Effect of Diode Laser, Gudmar and Vinegar in Diabetic Patients During Root Canal Treatment
| NCT ID | NCT07549373 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Sharda University |
| Condition | Diabete Type 2 |
| Study Type | INTERVENTIONAL |
| Enrollment | 90 participants |
| Start Date | 2026-05-01 |
| Primary Completion | 2026-12-31 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 90 participants in total. It began in 2026-05-01 with a primary completion date of 2026-12-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Methodology Patient with diabetes 2 with informed consent -convenience sampling over a one year period.The tooth isolated with a rubber dam and the correct disinfection procedures will be used. researcher will do the Access preparation Working length -electronic apex locator (Dentsply Propex II) as well as a radiographic approach. After the canals will be obturated using ZOE sealer and gutta percha and post endodontic restoration is done using composite restoration. Patient is kept on follow up for 7days, 15 days, 30 days ,45 days and 60 days Clinical outcome is measure using periapical radiograph (RVG) Pain is measured using visual analog scale to mark the pain intensity. Data will be analysed statistically To enlarge the root canals (ISO size 20 file) A sterile paper point inside the root canal for one minute until the apex of the root canal is reached Using T.E Buffer, samples will be delivered to the School Of Basic Life Sciences, Sharda University. The samples will be subjected to traditional PCR analysis for the detection of Peptostreptococcus spp. in the root canal. Grouping Following instrumentation, 5% NaOCl and 17% EDTA irrigation will be done. Control group (n=15) The final irrigant will be saline Group 1 (n=15) Irrigation using 5% apple cider vinegar done The final irrigant will be saline Group 2 (n=15) Diode laser is used for disinfection in the presence of saline Group 3 (n=15) Gymnema Sylvestre Mother Tincture Q 1000 CH solution is used for disinfection in the presence of saline Group 4 (n=15) Diode laser is used for disinfection in the presence of 5% apple cider vinegar. The final irrigant will be saline Group 5 (n=15) Diode laser is used for disinfection in the presence of Gymnema Sylvestre Mother Tincture Q 1000 CH solution. The final irrigant will be saline After cleaning and shaping, samples will be collected and sent through T.E. Buffer to the School Of Basic Life Sciences, Sharda University. The samples will be subjected to traditional PCR analysis for the detection of Peptostreptococcus spp. in the root canal.
Eligibility Criteria
Inclusion Criteria: * Using radiographs, intraoral periapical radiographs (RVG) primary endodontic infection will be selected. * Multirooted teeth , root with periapical lesion will be selected * Type 2 diabetics between the ages of 25 years and 60 years will be chosen; both male and female patients * A fasting blood sugar level of 126 mg/dl and a random blood sugar level of less than 200 mg/dl * HbA1c (glycated haemoglobin) ≥ 6.5% Exclusion Criteria: * Patients with systemic conditions other than type 2 diabetes * Women who are pregnant * Those patients that have used antibiotics within the previous three months, * Those patients that have teeth with developmental defects, calcified canals, * Teeth that cannot be isolated with rubber dams, * Tortuous canals * Roots that are fractured
Contact & Investigator
Dr Ekta Choudhary, MDS
STUDY DIRECTOR
School of Dental Sciences , Sharda University
Frequently Asked Questions
Who can join the NCT07549373 clinical trial?
This trial is open to participants of all sexes, aged 25 Years or older, up to 60 Years, studying Diabete Type 2. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07549373 currently recruiting?
Yes, NCT07549373 is actively recruiting participants. Contact the research team at drlakshmipandey024@gmail.com for enrollment information.
Where is the NCT07549373 trial being conducted?
This trial is being conducted at Noida, India.
Who is sponsoring the NCT07549373 clinical trial?
NCT07549373 is sponsored by Sharda University. The principal investigator is Dr Ekta Choudhary, MDS at School of Dental Sciences , Sharda University. The trial plans to enroll 90 participants.