NCT07808749 Effect of Cardiorespiratory Changes on Carotid Flow Time During Lung Resection Surgery
| NCT ID | NCT07808749 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University of Valencia |
| Condition | Hemodynamic Monitoring |
| Study Type | OBSERVATIONAL |
| Enrollment | 50 participants |
| Start Date | 2025-01-27 |
| Primary Completion | 2026-12-17 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 50 participants in total. It began in 2025-01-27 with a primary completion date of 2026-12-17.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Cardiorespiratory changes during lung resection surgery, even though generally well tolerated, may lead to hemodynamic compromise, reducing venous return to the heart and hence cardiac output. Carotid corrected flow time is widely regarded as non-invasive index of preload status, yet its dynamic relationship with cardiac output, especially in surgical population is not well-studied. Understanding how cardiorespiratory changes affect carotid flow time in anesthesized patients remains limited. This study investigates corrected carotid flow time response to anesthesia, lateral position, one-lung ventilation, open chest, capnothorax, lung recruitment and volume expansion, hypothesizing that cFT declines in association with CO reduction during lung resection. The secondary interest of the study is to test whether carotid flow time and its recruitment-induced change can adequately predict fluid response during one-lung ventilation. In addition, the baseline preoperative carotid flow time and its position-induced change are studied as potential predictors of hemodynamic tolerance to lung recruitment and fluid response, respectively. Finally, the purpose of this study is to see if cardiorespiratory changes and volume expansion affect cerebral blood volume during lung resection surgery.
Eligibility Criteria
Inclusion Criteria: * patients scheduled to undergo thoracosocpic lung resection surgery Exclusion Criteria: * carotid stenosis or abnormal anatomy of carotid artery that prevents visualization, emphysema, arrythmia
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07808749 clinical trial?
This trial is open to participants of all sexes, studying Hemodynamic Monitoring. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07808749 currently recruiting?
Yes, NCT07808749 is actively recruiting participants. Contact the research team at margry@uv.es for enrollment information.
Where is the NCT07808749 trial being conducted?
This trial is being conducted at Valencia, Spain.
Who is sponsoring the NCT07808749 clinical trial?
NCT07808749 is sponsored by University of Valencia. The trial plans to enroll 50 participants.