Effect of Boswellia Sacra as an Intracanal Medicament on Postoperative Pain Intensity and Bacterial Load Reduction
Trial Parameters
Brief Summary
This research will study the effect of Boswellia Sacra versus calcium hydroxide as an intracanal medicament on postoperative pain intensity measured using numerical rating scale (NRS) and bacterial load reduction reduction determined by bacterial counting using agar culture technique after root canal preparation (CFU/ml) in mandibular premolars with necrotic pulp.
Eligibility Criteria
Inclusion Criteria: 1. Age between 25-45 years old. 2. Males or females. 3. Healthy patients whom are categorized as I or II according to The American Society of Anesthesiologists. (ASA I or II) 4. Patients' accepting to participate in the trial. 5. Patients who can understand pain scale and can sign the informed consent. 6. Mandibular Single rooted premolars, having single root canal: * Diagnosed clinically with pulp necrosis. * Absence of spontaneous pulpal pain. * Positive pain on percussion denoting apical periodontitis. * Periapical radiolucency not exceeding 2\*2 mm radiographically. * Normal occlusal contact with opposing teeth. Exclusion Criteria: 1. Medically compromised patients having significant systemic disorders (ASA III or IV). 2. If analgesics or antibiotics have been administrated by the patient during the past 24 hours preoperatively as it might alter their pain perception. 3. Pregnant women: to avoid radiation exposure, anesthesia, medication and hormonal Fluctuation