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Recruiting Phase 2, Phase 3 NCT07252778

NCT07252778 Effect of a Short-term Multi-strain Probiotic Supplementation in Endurance Athletes

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Clinical Trial Summary
NCT ID NCT07252778
Status Recruiting
Phase Phase 2, Phase 3
Sponsor Krzysztof Durkalec-Michalski
Condition Sports Nutrition
Study Type INTERVENTIONAL
Enrollment 30 participants
Start Date 2025-11-20
Primary Completion 2027-06-01

Eligibility & Interventions

Sex Female only
Min Age 16 Years
Max Age 50 Years
Study Type INTERVENTIONAL
Interventions
MPRO supplementationPlacebo treatment

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

In Phase 2, researchers evaluate early signs of effectiveness. You may be randomized to receive the active treatment or a comparator. Monitoring continues closely.

This trial targets 30 participants in total. It began in 2025-11-20 with a primary completion date of 2027-06-01.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

The aim of this project is to evaluate and identify the effect of a short-term 2-week multi-strain probiotic (MPRO) supplementation on the exercise-associated gastrointestinal (GI) symptoms and perturbations in high level female athletes of the Polish national team during strictly controlled conditions of a training camp, based on recommendations for best practices for probiotic (PRO) research in athletes and assessment of EX-associated GI perturbations.

Eligibility Criteria

Inclusion Criteria: * belonging to the national rowing team; * training experience ≥5 years; * a currently issued medical certificate confirming * good health and capacity to practice sports; * good health without chronic health disorders; * written informed consent to participate. Exclusion Criteria: * injury, any health contraindication or failure to perform exercise procedures; * gastrointestinal infections, diseases, disorders; * past history of gastrointestinal surgery, and * other self-reported gastrointestinal issues; * reporting symptoms of infection or taking any medication (e.g. antibiotics) for 4 weeks before the study protocol; * current supplementation of prebiotics, * probiotics, synbiotics (last 4 weeks); * current intake of pharmaceutical agents (e.g., nonsteroidal anti-inflammatory drugs, laxatives, antidiarrhea agents, antacids, and/or antiemetics) (last 4 weeks); * failure to follow the study protocol; * declared general feeling of being unwell; * pregnancy or current pregnancy planning.

Contact & Investigator

Central Contact

Natalia Główka, PhD

✉ glowka@awf.poznan.pl

📞 +48 691 756 944

Principal Investigator

Krzysztof Durkalec-Michalski, PhD

STUDY CHAIR

Department of Sports Dietetics, Poznan University of Physical Education Poznań

Frequently Asked Questions

Who can join the NCT07252778 clinical trial?

This trial is open to female participants only, aged 16 Years or older, up to 50 Years, studying Sports Nutrition. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

What phase is the NCT07252778 trial and what does that mean for participants?

Phase 2 trials evaluate whether the treatment shows signs of effectiveness while continuing to monitor safety. More participants are enrolled than in Phase 1 to help refine the treatment protocol.

Is NCT07252778 currently recruiting?

Yes, NCT07252778 is actively recruiting participants. Contact the research team at glowka@awf.poznan.pl for enrollment information.

Where is the NCT07252778 trial being conducted?

This trial is being conducted at Poznan, Poland.

Who is sponsoring the NCT07252778 clinical trial?

NCT07252778 is sponsored by Krzysztof Durkalec-Michalski. The principal investigator is Krzysztof Durkalec-Michalski, PhD at Department of Sports Dietetics, Poznan University of Physical Education Poznań. The trial plans to enroll 30 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: September 2026  ·  Data Methodology