NCT07538726 Early Partial Weight-bearing May Improve Functional Recovery Without Increasing Complications Despite This Potential, Limited Randomized Studies Have Evaluated Early Weight-bearing After Pelvic Fixation Surgeries
| NCT ID | NCT07538726 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Assiut University |
| Condition | Pelvic Fractures |
| Study Type | INTERVENTIONAL |
| Enrollment | 50 participants |
| Start Date | 2025-08-31 |
| Primary Completion | 2026-05 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 50 participants in total. It began in 2025-08-31 with a primary completion date of 2026-05.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The goal of this randomized clinical trial is to compare between the effect of immediate weight bearing (WB) versus delayed weight bearing in improving function, pain, gait, quality of reduction radiologically, muscle strength, and quality of life outcomes in individuals who underwent specific pelvic fixation surgeries.
Eligibility Criteria
Inclusion Criteria: * Age ≥ 18 to 55 years * Traumatic fractures indicated for pelvic fixation. * All Types B after stable anterior and / or posterior fixation. * Type C, Stable fixation: Posterior fixation by triangular osteosynthesis. oTrans-iliac trans-sacral screw fixation or Trans iliac plate or posterior infex combined with anterior fixation. • Excellent to good quality of fracture reduction by Matta and Tornetta radiological assessment. Exclusion Criteria: * Associated lower extremity fractures that independently restrict or contraindicate weight-bearing activities. * Bilateral unstable after fixation pelvic ring disruption. * Patients with associated spinal cord injury, as neurological deficits may alter gait, functional recovery, and weight-bearing capacity, thereby affecting the validity and generalizability of the outcome measures. * Current history of acute systemic infection, active Bone inflammatory disease, (e.g., osteomyelitis, chronic non-bacterial osteitis), or malignancy, which may compromise the healing process, confound clinical outcomes, or pose additional medical risks during rehabilitation. * Uncontrolled Diabetes * Cancer * Active infection * Morbid obesity (BMI \> 40) * Alcohol use disorder (AUD). Alcohol abuse as defined by the National Institute on Alcohol Abuse and Alcoholism: "Drinking at Low Risk for Developing Alcohol Use Disorder: For women, low-risk drinking is defined as no more than 3 drinks on any single day and no more than 7 drinks per week. For men, it is defined as no more than 4 drinks on any single day and no more than 14 drinks per week. NIAAA research shows that only about 2 in 100 people who drink within these limits have AUD". * Claustrophobia * Pregnant woman * Inability to follow study protocol (e.g., lack of ability to attend visits or comprehend instructions) * Any psychiatric illness that would prevent comprehension of the details and nature of the study and interfere with follow-up clinical visits * Any clinical finding that would place the patient at health risk, impact the study, or affect the completion of the study
Contact & Investigator
Osama Ahmed Farouk, MD
STUDY DIRECTOR
Professor of Orthopedic and Trauma surgeries
Frequently Asked Questions
Who can join the NCT07538726 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 55 Years, studying Pelvic Fractures. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07538726 currently recruiting?
Yes, NCT07538726 is actively recruiting participants. Contact the research team at Hager.Emad@med.aun.edu.eg for enrollment information.
Where is the NCT07538726 trial being conducted?
This trial is being conducted at Asyut, Egypt.
Who is sponsoring the NCT07538726 clinical trial?
NCT07538726 is sponsored by Assiut University. The principal investigator is Osama Ahmed Farouk, MD at Professor of Orthopedic and Trauma surgeries. The trial plans to enroll 50 participants.