Trial Parameters
Brief Summary
Longitudinal cohort study; measurements before start of systemic therapy and one year later.
Eligibility Criteria
Inclusion Criteria: * Aged 18-39 years at cancer diagnosis * Having a histologically and/or cytologically confirmed cancer diagnosis, including leukemia, (non-)Hodgkin lymphoma, testicular cancer, osteosarcoma, Ewing sarcoma, breast cancer, and cervical cancer. * Scheduled to start systemic therapy with curative intent. Allowed treatments (concurrent or sequential) are: surgery, radiotherapy, chemotherapy, antibodies. Exclusion Criteria: * patients who are not able to understand the patient information letter and informed consent form * patients who will be treated with immune checkpoint inhibitors or targeted therapy with inhibitors of angiogenesis * patients who have been treated with systemic therapy or radiotherapy for a previous malignancy (exceptions: in situ carcinoma of the cervix or uterus and adequately treated basal and squamous cell carcinoma of the skin).