NCT07335692 Dynamical Electrophysiology and Neuropathology in Lewy's Bodies Disease
| NCT ID | NCT07335692 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University Hospital, Strasbourg, France |
| Condition | Lewy Body Disease |
| Study Type | OBSERVATIONAL |
| Enrollment | 40 participants |
| Start Date | 2025-06-02 |
| Primary Completion | 2026-06 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 40 participants in total. It began in 2025-06-02 with a primary completion date of 2026-06.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Lewy body disease (LBD) is a neurodegenerative disorder that causes cognitive and behavioral problems. However, it is difficult to diagnose, and its pathophysiology is still not fully understood. The usual diagnostic criteria for LBD have excellent specificity but poor sensitivity. In particular, we lack paraclinical tests that can make a significant contribution. LBD patients may exhibit abnormalities in brain activity dynamics, which can be detected by EEG and may be linked to neuronal dysfunctions specific to the disease. The objective of this study is twofold: first, to assess the validity of this observation, that is, to confirm that the observed phenomenon is indeed linked to the pathophysiology of LBD, and second, to clarify the nature of these abnormalities by exploring the brain dynamics of LBD patients in greater detail.
Eligibility Criteria
Inclusion Criteria: * Adult subjects (≥18 years old). * Subject who participated in the Alpha-Lewy-MA cohort and underwent RT-QuIC analysis. * Subject who underwent a standard EEG examination at HUS between January 1, 2012, and January 1, 2020. Exclusion Criteria: \- Subject who expressed opposition to participating in the study.
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07335692 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Lewy Body Disease. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07335692 currently recruiting?
Yes, NCT07335692 is actively recruiting participants. Contact the research team at ludovic.jeanjean@chru-strasbourg.fr for enrollment information.
Where is the NCT07335692 trial being conducted?
This trial is being conducted at Strasbourg, France.
Who is sponsoring the NCT07335692 clinical trial?
NCT07335692 is sponsored by University Hospital, Strasbourg, France. The trial plans to enroll 40 participants.