Dynamic Hormone Profiling and Multimodal Data Capture in Primary Aldosteronism
Trial Parameters
Brief Summary
This study is a observational study applying 24-hour microdialysis methodology to perform dynamic multisteroid adrenal hormone profiling of patients with suspected or confirmed PA. Simultaneous registration of blood pressure, tissue glucose, sleep pattern, activity level and food intake registration may be performed. The overall objective is to develop a novel, sensitive, fast and user-friendly diagnostic procedure for PA, using multimodal data capture including dynamic multisteroid hormone profiling from microdialysis fluid.
Eligibility Criteria
Inclusion criteria Age 18 to 70 years Suspected PA admitted for diagnostic saline infusion testing or confirmed PA diagnosis according to Endocrine Society criteria.. Written informed consent Exclusion criteria * Age \<18 or \> 70 years. * Pregnancy. * Known adrenal failure and/or on steroid therapy (oral, inhaled, parenteral or topical) or other interfering medication.