NCT07010380 Dual-Channel Near-Infrared Autofluorescence Imaging and AI Analysis to Locate Parathyroid Glands (PTFinder)
| NCT ID | NCT07010380 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Bo Wang,MD |
| Condition | Thyroid Neoplasms |
| Study Type | OBSERVATIONAL |
| Enrollment | 180 participants |
| Start Date | 2025-06-01 |
| Primary Completion | 2027-12-31 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 180 participants in total. It began in 2025-06-01 with a primary completion date of 2027-12-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This study tests PTFinder, a dual-camera system that makes parathyroid glands glow on screen by capturing their natural near-infrared autofluorescence. After a thyroid or parathyroid operation, the removed tissue is scanned with PTFinder and then checked again under normal white light. We will measure how fast (seconds) and how accurately the device finds real glands, confirmed by frozen pathology or a rapid PTH strip. About 180 adult patients at three Chinese hospitals will join. The imaging adds only a few minutes and does not change any part of the surgery. We will also record blood calcium and PTH at 1 h, 24 h, and 7 d after surgery to see whether better gland recovery lowers low-calcium risk.Collected images will also be used to train and test a deep-learning model for fully automated parathyroid recognition; model performance metrics constitute secondary outcomes.
Eligibility Criteria
Inclusion Criteria: * Age ≥18 years. * Scheduled for elective total thyroidectomy, hemithyroidectomy, or parathyroidectomy with removal of thyroid/parathyroid tissue. * Able and willing to provide written informed consent for participation and specimen imaging. Exclusion Criteria: * History of neck irradiation or prior neck surgery that may distort parathyroid anatomy. * Pregnancy or breastfeeding. * Confirmed or suspected parathyroid carcinoma, or thyroid carcinoma requiring en-bloc parathyroid resection. * Inability to understand the study procedures or to comply with follow-up.
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07010380 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Thyroid Neoplasms. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07010380 currently recruiting?
Yes, NCT07010380 is actively recruiting participants. Contact the research team at wangbo@fjmu.edu.cn for enrollment information.
Where is the NCT07010380 trial being conducted?
This trial is being conducted at Fuzhou, China.
Who is sponsoring the NCT07010380 clinical trial?
NCT07010380 is sponsored by Bo Wang,MD. The trial plans to enroll 180 participants.