NCT06361420 Driving Pressure-guided Lung Protective Ventilation
| NCT ID | NCT06361420 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Yong Lin, PhD |
| Condition | Hypoxemia |
| Study Type | INTERVENTIONAL |
| Enrollment | 43 participants |
| Start Date | 2024-01-26 |
| Primary Completion | 2025-12-31 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 43 participants in total. It began in 2024-01-26 with a primary completion date of 2025-12-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The study, named as "The Efficacy of Driving Pressure-guided Lung Protective Ventilation in Surgical Repair of Acute Type A Aortic Dissection: an open-label, randomized control clinical trial", aims to investigate whether driving pressure-guided lung protective ventilation can reduce postoperative oxygenation function in patients who have undergone surgical repair of acute type A aortic dissection. The primary outcomes is the incidence of postoperative hypoxemia (a partial pressure of arterial oxygen to inspiratory oxygen fraction ratio less than 300 mm Hg or a peripheral blood oxygen saturation less than 93% at any concentration of inspiratory oxygen) within 7 days after the surgery.
Eligibility Criteria
Inclusion Criteria: 1. Able to sign Informed Consent and Release of Medical Information Forms; 2. Age ≥ 14 years and ≤ 70 years old; 3. Being confirmed the diagnosis by chest computed tomography angiography and receiving the surgical repair of acute type A aortic dissection. Exclusion Criteria: 1. Age \< 14 years or \> 70 years old; 2. Sepsis before surgery; 3. Chronic pulmonary disease including lung infection or asthma requiring long-term pharmacotherapy; 4. History of lung tumor; 5. Obstructive sleep apnea hypopnea syndrome requiring long-term noninvasive mechanical ventilation support; 6. Heart failure requiring catecholamines or invasive mechanical ventilation support; 7. Body mass index \> 30 Kg·m-2; 8. Being reluctance to participate this study.
Contact & Investigator
Yong Lin, MD
PRINCIPAL INVESTIGATOR
Fujian Medical University Union Hospital
Frequently Asked Questions
Who can join the NCT06361420 clinical trial?
This trial is open to participants of all sexes, aged 14 Years or older, up to 70 Years, studying Hypoxemia. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06361420 currently recruiting?
Yes, NCT06361420 is actively recruiting participants. Contact the research team at birdman1983@163.com for enrollment information.
Where is the NCT06361420 trial being conducted?
This trial is being conducted at Fuzhou, China.
Who is sponsoring the NCT06361420 clinical trial?
NCT06361420 is sponsored by Yong Lin, PhD. The principal investigator is Yong Lin, MD at Fujian Medical University Union Hospital. The trial plans to enroll 43 participants.