NCT06134609 Does Sexual Intercourse Affect the Outcomes of Frozen-thawed Embryo Transfer?
| NCT ID | NCT06134609 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Sheba Medical Center |
| Condition | Embryo Transfer |
| Study Type | INTERVENTIONAL |
| Enrollment | 656 participants |
| Start Date | 2023-11-13 |
| Primary Completion | 2026-11 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 656 participants in total. It began in 2023-11-13 with a primary completion date of 2026-11.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The goal of this clinical trial is to test whether sexual intercourse the night after embryo transfer affects thawed embryo implantation rates. Women undergoing one of their first four frozen embryo transfers with a good quality embryo will be randomly assigned to two groups. The study group is subjected to have intercourse without using a condom at the evening/night after the embryo transfer, while the control group will abstain from intercourse for the next 48 hours after the transfer. Researchers will compare the ongoing pregnancy rates between the intervention group and the control group.
Eligibility Criteria
Inclusion Criteria: 1. Women age 18-41yrs. 2. BMI (body mass index) of 18-35 kg/m². 3. Patients undergoing one of their first four frozen embryo transfers. 4. Patients transferring a good quality embryo, either a cleavage stage embryo or a day 5 blastocyst. Exclusion Criteria: 1. Patients age above 42. 2. Moderate or poor-quality embryos. 3. Patients with hydrosalpinx or uterus malformations. 4. Patients who are not able or are not interested in having vaginal intercourse (same sex couples for example). 5. Couples undergoing preimplantation genetic diagnosis when natural cycle frozen embryo transfer is planned (as they are instructed to avoid intercourse).
Frequently Asked Questions
Who can join the NCT06134609 clinical trial?
This trial is open to female participants only, aged 18 Years or older, up to 41 Years, studying Embryo Transfer. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06134609 currently recruiting?
Yes, NCT06134609 is actively recruiting participants. Visit ClinicalTrials.gov or contact Sheba Medical Center to inquire about joining.
Where is the NCT06134609 trial being conducted?
This trial is being conducted at Ramat Gan, Israel.
Who is sponsoring the NCT06134609 clinical trial?
NCT06134609 is sponsored by Sheba Medical Center. The trial plans to enroll 656 participants.