← Back to Clinical Trials
Recruiting Phase 1, Phase 2 NCT06467318

Does Non-Steroidal Anti-inflammatory Drugs Decrease the Quality of Pleurodesis After Mechanical Pleural Abrasion/Pleurectomy for Treatment of Pneumothorax?

Trial Parameters

Condition Primary and Secondary Spontaneous Pneumothorax
Sponsor Ain Shams University
Study Type INTERVENTIONAL
Phase Phase 1, Phase 2
Enrollment 116
Sex ALL
Min Age N/A
Max Age N/A
Start Date 2023-09-01
Completion 2024-09
Interventions
ParacetamolNSAID, Paracetamol

Brief Summary

Investigators aim to assess if NSAIDs affect the quality of pleurodesis resulting from mechanical pleurodesis (open surgery or VATS) regarding : Primary outcome: Recurrence of pneumothorax in 6 monthes. (assessed by X ray after 2 weeks and 6 months or symptoms requiring X ray at any timing) Secondary outcome: ▪ Adjusted Length of stay ( from day zero surgery day to discharge ). ▪ Time of removal of the chest Tube .(relatively longer with air leak presence). ▪ Need of opioids (N-SAID may decrease the need of opioids) .

Eligibility Criteria

Inclusion Criteria: * Patients presented with primary or secondary spontaneous pneumothorax * Age: All age groups are included * Approach: Open and Video assisted thoracoscopic surgery ( Open and VATS pleurodesis). Exclusion Criteria: * Refusal of procedure or participation in the study. * Patient with any contra indication for NSAID (bleeding tendency , CKD , gastritis , allergy to NSAID ,…..)

Related Trials