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Recruiting NCT06651788

NCT06651788 Does Ethyl Chloride Spray Work?

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Clinical Trial Summary
NCT ID NCT06651788
Status Recruiting
Phase
Sponsor University of Chicago
Condition Injection Fear
Study Type INTERVENTIONAL
Enrollment 300 participants
Start Date 2025-04-01
Primary Completion 2027-12-31

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age N/A
Study Type INTERVENTIONAL
Interventions
Ethyl ChlorideCold Saline Spray

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

This trial targets 300 participants in total. It began in 2025-04-01 with a primary completion date of 2027-12-31.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

A procedure frequently performed by orthopaedic providers is the administration of corticosteroid injections for the management of various soft tissues and joint-related conditions, such as osteoarthritis, tendinitis, carpal tunnel syndrome, trigger finger, and de Quervain's tenosynovitis. While these injections have demonstrated effectiveness in alleviating symptoms, the discomfort associated with the procedure can be a source of anxiety and apprehension for patients. This discomfort arises from the sensation of the needle entering the affected area and the burning sensation induced by the corticosteroid solution.

Eligibility Criteria

Inclusion Criteria: * 18 years and older * Receiving a corticosteroid injection in an upper or lower extremity (to include soft tissue and joint injections) for the first time Exclusion Criteria: * Patients with previous injection experiences

Contact & Investigator

Central Contact

Jennifer M Wolf, MD, PhD

✉ jwolf@bsd.uchicago.edu

📞 773-834-3531

Frequently Asked Questions

Who can join the NCT06651788 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, studying Injection Fear. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT06651788 currently recruiting?

Yes, NCT06651788 is actively recruiting participants. Contact the research team at jwolf@bsd.uchicago.edu for enrollment information.

Where is the NCT06651788 trial being conducted?

This trial is being conducted at Chicago, United States.

Who is sponsoring the NCT06651788 clinical trial?

NCT06651788 is sponsored by University of Chicago. The trial plans to enroll 300 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: September 2026  ·  Data Methodology