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Recruiting NCT06311305

Does Early Laparoscopic Cholecystectomy After ERCP Reduce the Risk of Complications

Trial Parameters

Condition Cholelithiases
Sponsor Sohag University
Study Type INTERVENTIONAL
Phase N/A
Enrollment 30
Sex ALL
Min Age 15 Years
Max Age 70 Years
Start Date 2024-03-01
Completion 2024-08-01
Interventions
Early Laparoscopic cholecystectomy

Brief Summary

Gallstones have been recognised since antiquity and have been found during autopsies of Egyptian mummies. Following the first successful open cholecystectomy in 1882, it was Eric Muhe, a German surgeon, who performed the first laparoscopic cholecystectomy (Lapara, the flank; and skopein, to examine) in 1985. The common mechanism of gallstone formation includes cholesterol hypersecretion, alteration in intestinal bile salt, cholesterol absorption and gall bladder hypokinesia, which leads to bile cholesterol supersaturation and nucleation. Incidence of CBD stones in cases of cholelithiasis is around 3.4%-15%.2 Choledocholithiasis can either be primary or secondary. Secondary Choledocholithiasis being more common occurs due to stones originating in gallbladder and then migrating through cystic duct to CBD. Primary bile duct stones originate from within bile ducts and are more common in Asian populations. These stones are associated with biliary stasis and bacteria.

Eligibility Criteria

Inclusion Criteria: * Patients post ERCP with gall stone. * Age 15-70 * Gender female and male patient. Exclusion Criteria: * Post ERCP pancreatitis * Septicemia * Hepatocellular jaundice and End stage liver disease * Patient who didn't give informed consent. * Patients who refused laparoscopic cholecystectomy. * Patients who were not fit for general anesthesia due to various medical illnesses. * ERCP for reasons other than stone disease, * Contraindications to Laparoscopic cholecystectomy like: Cardiovascular andpulmonary disease, coagulopathies and end-stage liver disease (ESLD). * Patients with Carcinoma Gall bladder, Common bile duct strictures, Coagulopathy, previous upper abdominal surgeries

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