Do Patients Who Received Tranexamic Acid in Vaginal Hysterectomy Loose Les Blood, Comparing to Patients Who Did Not?
Trial Parameters
Brief Summary
This is a randomized control, double-blind study in which women who are about to go an elective vaginal hysterectomy are offered to participate. Patients will be randomly assigned to one of two groups: the tranexamic acid group, in which 1 gram of tranexamic acid (Hexakapron) is administered intravenously before surgery, and the control group, in which patients will receive 10 ml of normal saline 0.9% intravenously.
Eligibility Criteria
Inclusion Criteria: \*Women in general good health (defined as American Society of Anesthesiologists grade 1-2) who are about to undergo elective vaginal hysterectomy indicated by pelvic organ prolapse (POP). Exclusion Criteria: * allergy to TXA * familial or personal history of hypercoagulability disorder or thromboembolic events * impaired renal function or hematuria * patients receiving antithrombotic therapy * additional concurrent abdominal/ laparoscopic procedures * malignancy * Post-assignment exclusion will be executed in cases of conversion to laparotomy/ laparoscopy.