NCT07253948 Distribution Characteristics of Helicobacter Pylori
| NCT ID | NCT07253948 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Jilin University |
| Condition | Helicobacter Pylori |
| Study Type | OBSERVATIONAL |
| Enrollment | 231 participants |
| Start Date | 2025-10-22 |
| Primary Completion | 2025-12-31 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 231 participants in total. It began in 2025-10-22 with a primary completion date of 2025-12-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This study aimed to analyze the distribution characteristics of Helicobacter pylori（H. pylori） in varying stages of atrophic gastritis and early gastric cancer using immunohistochemical staining, with the goal of providing guidance for the early screening of gastric cancer. A retrospective analysis was conducted on gastric biopsy cases that underwent H. pylori immunohistochemical staining at our center from March 1, 2023, to August 15, 2025. Cases were classified into non-atrophic and atrophic groups based on the presence or absence of gastric atrophy. All cases were further divided into non-open and open atrophy groups and additionally into early gastric cancer and non-cancer groups. The distribution of H. pylori across subgroups was compared, and multivariate analyses were performed to identify risk factors associated with the development of early gastric cancer.
Eligibility Criteria
Inclusion Criteria: * age 18-80 years * received H. pylori immunohistochemical testing at our center and tested positive. Exclusion Criteria: * biopsies not collected from both the greater and lesser curvatures of the gastric antrum and body * history of stomach surgery * suspected autoimmune gastritis under endoscopy * liver cirrhosis * severe comorbidities such as advanced cancer or renal failure * advanced gastric cancer or gastric lymphoma
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07253948 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 80 Years, studying Helicobacter Pylori. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07253948 currently recruiting?
Yes, NCT07253948 is actively recruiting participants. Contact the research team at 714488468@qq.com for enrollment information.
Where is the NCT07253948 trial being conducted?
This trial is being conducted at Changchun, China.
Who is sponsoring the NCT07253948 clinical trial?
NCT07253948 is sponsored by Jilin University. The trial plans to enroll 231 participants.