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Recruiting NCT06774430

Digital Strategies to Advance Help-Seeking Aim 1 and 2

Trial Parameters

Condition Clinical High Risk
Sponsor Columbia University
Study Type OBSERVATIONAL
Phase N/A
Enrollment 25,000
Sex ALL
Min Age 12 Years
Max Age 29 Years
Start Date 2025-04-07
Completion 2028-05-31

Brief Summary

This proposal aims to establish a Digital Laboratory focused on advancing help-seeking and expediting treatment initiation in youth ages 12-29 who are at Clinical High-Risk (CHR) for developing psychosis. Leveraging the Health Action Process Approach (HAPA) model, this study will identify help-seeking subtypes in 25,000 youth who screen positive for psychosis-risk on Mental Health America's national online screening platform, iteratively develop and test theory and data-driven, personalized strategies to advance help-seeking using Micro-Randomized Trials and a Sequential Multiple Assignment Randomized Trial, identify the most accurate CHR screening threshold in an online environment, and link youth, when indicated, to local clinical care via Accelerating Medicines Partnership - Schizophrenia (AMP-SCZ), a NIH funded national network of CHR programs throughout the US. This academic-industry partnership aims to curate one of the largest datasets of youth with CHR, and to develop effective strategies to enhance early help-seeking, in a population where help-seeking is critical and a significant barrier to care.

Eligibility Criteria

Inclusion Criteria: * Ages 12-29 years * Living within a 50-mile radius of a US based AMP-SCZ site * Able to complete the English language PQ-B on MHA's screening platform

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