NCT07313995 Digital Health Intervention to Improve TPT Uptake
| NCT ID | NCT07313995 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Arba Minch University |
| Condition | Tuberculosis, Pulmonary |
| Study Type | INTERVENTIONAL |
| Enrollment | 304 participants |
| Start Date | 2026-05-22 |
| Primary Completion | 2026-09-22 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 304 participants in total. It began in 2026-05-22 with a primary completion date of 2026-09-22.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Despite the evidence of the prevention and control measures of tuberculosis (TB), it still has an impact on the health, social, and economic aspects of the population. Specifically, tuberculosis in children and newly diagnosed TB cases show there is current transmission of TB; to reduce this transmission and to attain the end TB strategy, preventing household TB transmission plays a great role. However, initiation and completion of TB preventive therapy (TPT) among close contacts of index TB patients are suboptimal. Some of the identified factors of low TPT initiation and completion are insufficient patient education, inadequate understanding of TPT, health professionals' perception, parental knowledge, and belief. The digital health intervention is currently being studied as a suggested health intervention that improves the utilization of health care services, including treatment adherence. A systematic review shows that TB treatment outcomes improved with the use of patient education, counseling, text reminders, and digital health technologies. However, other literature indicates controversial results, including our systematic review result, which identified that video directly observed therapy and text message (digital intervention) have no significant effect on TPT completion. In addition, the studies are scarce; therefore, this study aims to assess the effect of video-based education intervention combined with text message reminder (digital health intervention) in improving the initiation and completion of TPT among close contacts of drug-sensitive pulmonary TB patients in South Ethiopia. The study hypothesizes that digital health intervention for close contacts of index drug-sensitive pulmonary TB patients will lead to higher TPT initiation and completion rates than standard care.
Eligibility Criteria
Inclusion Criteria: * All household and close contacts of drug-sensitive pulmonary TB patients * Living in the catchment area of the selected health facility * Willing to stay for at least 4 months in the catchment area Exclusion Criteria: * Individuals with a known allergy to TPT drugs or those contraindicated for TPT drugs * Close contacts screened as symptomatic for TB * Close contacts with drug-resistant TB * Temporary residents staying for less than 4 months
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07313995 clinical trial?
This trial is open to participants of all sexes, studying Tuberculosis, Pulmonary. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07313995 currently recruiting?
Yes, NCT07313995 is actively recruiting participants. Contact the research team at ayelegistane@yahoo.com for enrollment information.
Where is the NCT07313995 trial being conducted?
This trial is being conducted at Arba Minch, Ethiopia, Sawula, Goffa Zone, Ethiopia.
Who is sponsoring the NCT07313995 clinical trial?
NCT07313995 is sponsored by Arba Minch University. The trial plans to enroll 304 participants.