NCT05709600 Dietary Interventions During Living Kidney Donations
| NCT ID | NCT05709600 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University of Cologne |
| Condition | Living-Kidney Donors |
| Study Type | INTERVENTIONAL |
| Enrollment | 80 participants |
| Start Date | 2023-02-01 |
| Primary Completion | 2027-06-30 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 80 participants in total. It began in 2023-02-01 with a primary completion date of 2027-06-30.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Monocentre, non-randomized, non-blinded, open-label interventional study to identification of relevant changes in molecular biology in proteome, phosphoproteome, lipidome, epigenome and transcriptome in pretransplant kidney biopsy samples in patients preconditioned by different dietary regimes (fasting mimicking diet vs. ketogenic diet vs. dietary restriction of sulfur containing amino acids vs. control patients)
Eligibility Criteria
Inclusion Criteria: * Patients \> 18 years of age * Planed living kidney transplantation (both donor and recipient are eligible) * Written informed consent Exclusion Criteria: * Vegetarian lifestyle * Body-Mass-Index (BMI) \< 18.5 kg/m2 * Calorie-reduced diet within the preceding four weeks * Underlying wasting syndrome * Contraindication for enteral nutrition * Known allergy to or intolerance of the ingredients of the diet used * Pregnancy * Breastfeeding * Absence of safe contraceptive measures or non-occurrence of menopause (in women) * Participation in other interventional trials
Contact & Investigator
Roman-Ulrich Müller, Prof. MD
PRINCIPAL INVESTIGATOR
Department II of Internal Medicine, University Hospital of Cologne
Frequently Asked Questions
Who can join the NCT05709600 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Living-Kidney Donors. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT05709600 currently recruiting?
Yes, NCT05709600 is actively recruiting participants. Contact the research team at felix.koehler@uk-koeln.de for enrollment information.
Where is the NCT05709600 trial being conducted?
This trial is being conducted at Cologne, Germany.
Who is sponsoring the NCT05709600 clinical trial?
NCT05709600 is sponsored by University of Cologne. The principal investigator is Roman-Ulrich Müller, Prof. MD at Department II of Internal Medicine, University Hospital of Cologne. The trial plans to enroll 80 participants.
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